Citation Information :
Hata T, Koyanagi A, Konishi M, Miyagi Y, Miyake T. Fetal Cardiac Size and Shape Assessed by HDlive Flow with Spatiotemporal Image Correlation at 11–13+6 Weeks of Gestation. Donald School J Ultrasound Obstet Gynecol 2024; 18 (4):323-327.
Objective: To assess fetal cardiac size and shape using HDlive Flow with spatiotemporal image correlation (STIC) at 11–13+6 weeks of gestation.
Materials and methods: During the 4 months from December 2021 to March 2022, HDlive Flow with STIC examinations were performed for 72 normal fetuses at 11–13+6 weeks. The spatial basal-apical length (BAL), transverse length (TL), fetal cardiac circumference (FCC), fetal cardiac area (FCA), and global sphericity index (GSI) were investigated. Reference ranges were also created.
Results: Spatial BAL, TL, FCC, and FCA increased linearly with gestation (r = 0.5762, 0.6746, 0.6543, and 0.6412, respectively, p < 0.001). Spatial GSI (mean, 1.1755; SD, 0.1413) values were gradually decreasing at 11–13+6 weeks of gestation, but this was not significant (r = –0.1735, p = 0.167).
Conclusion: The current results provide basic information to advanced understanding of fetal cardiac growth and development at 11–13+6 weeks of gestation.
Ito M, AboEllail MAM, Yamamoto K, et al. HDlive Flow silhouette mode and spatiotemporal image correlation for diagnosing congenital heart disease. Ultrasound Obstet Gynecol 2017;50:411–415. DOI: 10.1002/uog.17519
Hata T, Koyanagi A, Yamanishi T, et al. Success rate of five fetal cardiac views using HDlive Flow with spatiotemporal image correlation at 18–21 and 28–31 weeks of gestation. J Perinat Med 2020;48:384–388. DOI: 10.1515/jpm-2019-0434
Hata T, Koyanagi A, Kawahara T, et al. HDlive Flow silhouette with STIC for assessment of fetal cardiac structures at 12–14+6 weeks of gestation. J Perinat Med 2021;50:313–318. DOI: 10.1515/jpm-2021-0252
Hata T, Koyanagi A, Kawahara T, et al. Fetal cardiac structure, shape, and aortic tortuosity at 15–17+6 weeks of gestation: HDlive Flow study. Donald Sch J Ultrasound Obstet Gynecol 2022;16:272–277. DOI: 10.5005/jp-journals-10009-1951
Hata T, Konishi M, Koyanagi A, et al. Embryonic and fetal heart development before 12 weeks of gestation. J Ultrasound Med 2024. DOI: 10.1002/jum.16605
Okai T. Standard values of ultrasonic measurements in Japanese fetuses. J Med Ultrason 2003;30:J415–J440.
Royston P, Wright EM. How to construct “normal ranges” for fetal variables. Ultrasound Obstet Gynecol 1998;11:30–38. DOI: 10.1046/j.1469-0705.1998.11010030.x
Merce LT, Barco MJ, Bau S. Reproducibility of the study of placental vascularization by three-dimensional power Doppler. J Perinat Med 2004;32:228–233. DOI: 10.1515/JPM.2004.043
Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;1:307–310.
DeVore GR, Satou G, Sklansky M. Abnormal fetal findings associated with a global sphericity index of the 4-chamber view below the 5th centile. J Ultrasound Med 2017;36:2309–2318. DOI: 10.1002/jum.14261
Wang D, Liu C, Liu X, et al. Evaluation of prenatal changes in fetal cardiac morphology and function in maternal diabetes mellitus using a novel fetal speckle-tracking analysis: a prospective cohort study. Cardiovasc Ultrasound 2021;19:25. DOI: 10.1186/s12947-021-00256-z
Zhang P, Fu X, Zhao L, et al. Quantifying fetal heart health in gestational diabetes: a new approach with fetal heart quantification technology. Front Pharmacol 2024;15:1394885. DOI: 10.3389/fphar.2024.1394885