Background: One in five women of reproductive age-group is affected by polycystic ovarian syndrome (PCOS). The high prevalence of PCOS makes it of immense clinical and public health importance. This study is aimed to compare the clinical, radiological, hormonal, and metabolic parameters of nonobese and overweight PCOS patients. Aim: This prospective observational study is aimed to compare the clinical, radiological, hormonal, and metabolic parameters of nonobese and overweight PCOS patients. Materials and methods: This prospective observational study is conducted among the patients attending the outpatient department (OPD) diagnosed with PCOS according to Rotterdam's criteria among females aged 15–45 years (reproductive age-group). A total of 57 participants are included in the study. All participants fulfilled the inclusion criteria and informed consent was obtained. Results: The mean age of participants was found to be 22.3 ± 4.4 years of age. There was a significantly higher mean weight and waist-hip ratio among the group II participants compared to group I (p < 0.05). The mean level of luteinizing hormones (LH) among group II was 11.81 ± 4.67 and group I was 10.58 ± 4.47 (p > 0.05) and thyroid-stimulating hormone (TSH) levels were 2.93 ± 1.91 among group II and 3.07 ± 2.12 among group I participants (p > 0.05). The mean stromal volume of the right ovary in group II was 13.5 ± 4.2 and in group I was 12.2 ± 3.4 and of the left ovaries, it was 12.05 ± 3.05 in group II and 11.30 ± 2.78 in group I participants (p > 0.05). The significantly higher mean of total cholesterol among group II (170.7 ± 22.7 mg/dL) compared to group I participants (155.8 ± 21.1 mg/dL) (p < 0.05). Hirsutism was significantly higher among group II participants (27.8%) compared to the participants in group I (p < 0.05). Conclusion: It was found that there is a significant difference in the metabolic parameters and clinical characteristics in the PCOS women of both groups and also a significantly higher incidence of hirsutism among the obese PCOS participants, as well as a higher incidence of other clinical parameters.