Donald School Journal of Ultrasound in Obstetrics and Gynecology

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VOLUME 15 , ISSUE 1 ( January-March, 2021 ) > List of Articles

PROSPECTIVE COHORT STUDY

First-trimester 3D Power Doppler of Uteroplacental Circulation and Placental Volume for the Prediction of Preeclampsia: A Prospective Cohort Study

Mohamed S Sweed, Gasser A El-Bishry, Amgad E Abou-Gamrah, Mohamed M AbdEl-Hamid, Eman A NasrEl-Din, Gihan E El-Hawwary

Keywords : Cohort studies, Doppler, Duplex, Imaging, Placenta, Preeclampsia, Three-dimensional, Ultrasonography

Citation Information : Sweed MS, El-Bishry GA, Abou-Gamrah AE, AbdEl-Hamid MM, NasrEl-Din EA, El-Hawwary GE. First-trimester 3D Power Doppler of Uteroplacental Circulation and Placental Volume for the Prediction of Preeclampsia: A Prospective Cohort Study. Donald School J Ultrasound Obstet Gynecol 2021; 15 (1):109-113.

DOI: 10.5005/jp-journals-10009-1681

License: CC BY-NC 4.0

Published Online: 00-03-2021

Copyright Statement:  Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim and objective: To evaluate the role of first-trimester 3D power Doppler of placental circulation and placental volume in the prediction of poor pregnancy outcomes. Materials and methods: This prospective cohort study included 375 pregnant women. 3D scans for the determination of placental volume and vascularization indices were performed. The primary outcome was the occurrence of preeclampsia (PE). Results: Placental 3D power Doppler indices were significantly lower in women who developed PE [vascularization index (VI) = 3.13 ± 2.1, flow index (FI) = 14.9 ± 9.3, vascularization flow index (VFI) = 0.1 ± 0.9] and fetal growth restriction (FGR) (VI = 4.5 ± 2.4, FI = 15.3 ± 7.9, VFI = 0.3 ± 0.6) compared with those who did not (VI = 9.7 ± 1.9, FI = 28.9 ± 4.6, VFI = 1.8 ± 1.4) (VI = 10.9 ± 1.6, FI = 30.9 ± 7.6, VFI = 1.9 ± 0.9), respectively (p < 0.001). The cutoff values for the prediction of PE were VI ≤ 3.22, FI ≤ 17.73, and VFI ≤ 0.5, while those for the prediction of intrauterine FGR were VI ≤ 4.12, FI ≤ 15.93, and VFI ≤ 0.3. Conclusion: First-trimester evaluation of placental bed vasculature with 3D power Doppler can be used as a good predictor of PE. Clinical significance: First-trimester 3D power Doppler of placental bed vasculature can help early prediction of PE and FGR allowing early intervention giving opportunity for better pregnancy outcomes.


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