Citation Information :
Singh A, Singh G, Gupta K. Estimation of Gestational Age by Using Fetal Kidney Length and Transcerebellar Diameter in Comparison with Other Biometric Indices. Donald School J Ultrasound Obstet Gynecol 2021; 15 (1):4-9.
Background: The knowledge of accurate estimation of gestational age (GA) for an obstetrician is first and foremost to date the pregnancy as early as possible during the antenatal period for proper management of all the pregnancies. Ultrasound parameters like BPD, HC, AC and FL in second and third trimesters are not very reliable for dating the pregnancy. Fetal kidney length (FKL) and transcerebellar diameter (TCD) have been studied and shown to strongly correlate with the gestational age. Materials and methods: A prospective observational study was conducted on 600 women with normal singleton pregnancies. Fetal kidney length and transcerebellar diameter were measured using Voluson E8 (Wipro GE) ultrasound machine. Statistical analysis was done using tests of correlation and simple linear regression. All analysis was done by using SSPS statistics 24.0. Results: The result indicates that the fetal kidney length and transcerebellar diameter in the present study correlated well with the assigned gestational age. A positive linear relationship of gestational age with fetal kidney length and transcerebellar diameter was found. Correlation of gestational age with fetal kidney length and transcerebellar diameter was 0.875 and 0.975 respectively. Conclusion: The present study reveals that fetal kidney length and transcerebellar diameter can be used as parameters in estimating gestational age, especially in later trimesters, where biometric indices may not be much reliable.
Dutta DC. Diagnosis of pregnancy. In: Konar H, ed. Textbook of Obstetrics. Kolkatta: New Central Book Agency (P) Ltd; 2004. pp. 73–74.
Kumar M, Lalwani R, Babu R, et al. Ultrasonographic estimation of fetal gestational age by fetal kidney length. J Anat Soc India 2013;62(1):33–36. DOI: 10.1016/S0003-2778(13)80009-3.
Konje J, Abrams K, Bell S, et al. Determination of gestational age after the 24th week of gestation from fetal kidney length measurements. Ultrasound Obstet Gynecol 2002;19(6):592–597. DOI: 10.1046/j.1469-0705.2002.00704.x.
Kaul I, Menia V, Anand AK. Role of fetal kidney length in estimation of gestational age. JK Science 2012;14(2):65–69.
Reddy D, Suma K. Correlation between fetal kidney length and fetal biometry for gestational age determination in third trimester in low-risk pregnancy. J SAFOG 2017;9(4):404–406. DOI: 10.5005/jp-journals-10006-1538.
Lemer J. Fetal growth and well being. Obstet Gynecol Clin of North Am 2004;31(1):159–176.
Degani S. Fetal biometry: Clinical, pathological, and technical considerations. Obstet Gynecol Surv 2001;56(3):159–167. DOI: 10.1097/00006254-200103000-00023.
Reddy R. Significance of foetal transcerebellar diameter in foetal biometry: a pilot study. J Clin Diagnos Res 2017;11(6):1–4. DOI: 10.7860/JCDR/2017/23583.9968.
Peter M, Nayak A, Giri P, et al. Fetal kidney length as a parameter for determination of gestational age from 20th week to term in healthy women with uncomplicated pregnancy. Int J Res Med Sci 2017;5(5):1869–1873. DOI: 10.18203/2320-6012.ijrms20171808.
Sharma R. Comparative accuracy of transcerebellar diameter and crown rump length for estimation of gestational age. Int J Med Imag 2017;5(3):38–41. DOI: 10.11648/j.ijmi.20170503.12.
Mahony B, Callen P, Filly R. The distal femoral epiphyseal ossification center in the assessment of third-trimester menstrual age: sonographic identification and measurement. Radiology 1985;155(1):201–204. DOI: 10.1148/radiology.155.1.3883417.
Konje JC, Okara CL, Bell SC, et al. A cross-sectional study of changes in fetal renal size with gestation in appropriate and small for gestational age fetuses. Ultrasound Obstet Gynecol 1997;9(1):35–37. DOI: 10.1046/j.1469-0705.1997.10010022.x.
Duval JM, Milon J, Langella B, et al. Ultrasonographic anatomy and physiology of the fetal kidney. Anat Clin 1985;7(2):107–123. DOI: 10.1007/BF01655512.
Sato A, Yamaguchi Y, Liou SM, et al. Growth of fetal kidney assessed by real time ultra sound. Eur Urol 1990;17(1):62–65. DOI: 10.1159/000464002.
Cohen HL, Cooper J, Eisenberg P, et al. Normal length of fetal kidneys: sonographic study in 397 obstetric patients. AJR Am J Roentgenology 1991;157(3):545–548. DOI: 10.2214/ajr.157.3.1872242.
Ansari SM, Saha M, Paul AK, et al. Ultrasonographic study of 793 foetuses: measurement of normal fetal kidney lengths in Bangladesh. Australas Radio 1997;41(1):3–5. DOI: 10.1111/j.1440-1673.1997.tb00457.x.
Afroz S, Hussain R. Length of the foetal kidneys: a correlation with gestational age. Bangl J Ultrasono 1996;3:2.
Kansaria JJ, Parulekar SV. Nomogram for fetal kidney length. Bombay Hosp J 2009;51(2):155–162.
Bharatnur S, Dawson S, Hebbar S. Kidney length, a visceral parameter predicts foetal age between 24 to 40 weeks of gestation. Int J Reproduct, Contracept, Obstetr Gynecol 2019;8(2):492–497. DOI: 10.18203/2320-1770.ijrcog20190273.
Swaminathan M, Davies M, Davis P, et al. Transverse cerebellar diameter on cranial ultrasound scan in pretermneonates in an Australian population. J Paediatr Child Health 1999;35(4):346–349. DOI: 10.1046/j.1440-1754.1999.00365.x.
Chavez MR, Ananth CV, Smulian JC, et al. Fetal transcerebellar diameter measurement for prediction of gestational age at the extremes of fetal growth. J Ultrasound Med 2007;26(9):1167–1171. DOI: 10.7863/jum.2007.26.9.1167.
Scott JA, Hamzelou KS, Rajagopalan V, et al. 3D morphometric analysis of human fetal cerebellar development. Cerebellum 2012;11(3):761–770. DOI: 10.1007/s12311-011-0338-2.
Goldstein I, Reece EA, Pilu G, et al. Cerebellar measurements with ultrasonography in the evaluation of fetal growth and development. Am J Obstet Gynecol 1987;156(5):1065–1067. DOI: 10.1016/0002-9378(87)90111-6.
Mcleary RD, Kuhns LR, Barr M. Ultrasonography of the fetal cerebellum. Radiology 1984;151(2):439–442. DOI: 10.1148/radiology.151.2.6709916.
Bansal M, Bansal A, Jain S, et al. A study of correlation of transverse cerebellar diameter with gestational age in the normal & growth restricted fetuses in western Uttar Pradesh. PJSR 2014;7(2):16–21.