Donald School Journal of Ultrasound in Obstetrics and Gynecology

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VOLUME 16 , ISSUE 1 ( January-March, 2022 ) > List of Articles

Observational Study

An Observational Study to Evaluate Single Deepest Vertical Pocket (SDP) and Color Doppler Indices (CDI) with Severity of Covid in Pregnant Women with COVID-19

Amita Azad, Astha Lalwani, Rehana Najam

Keywords : COVID-19, Doppler findings, SDP

Citation Information : Azad A, Lalwani A, Najam R. An Observational Study to Evaluate Single Deepest Vertical Pocket (SDP) and Color Doppler Indices (CDI) with Severity of Covid in Pregnant Women with COVID-19. Donald School J Ultrasound Obstet Gynecol 2022; 16 (1):19-24.

DOI: 10.5005/jp-journals-10009-1911

License: CC BY-NC 4.0

Published Online: 22-04-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Aim: The present study was done for the assessment of the single deepest vertical pocket (SDP) and color Doppler indices (CDI) among COVID positive pregnant women to decide upon further management. Materials and method: A total of 102 patients were enrolled. The data collection was done by a single examiner following the protocol for the study. The study included confirmed COVID-19 positive pregnant patients. The inclusion standards were singleton pregnancy along with gestational age 28 weeks onward. Patients were divided on the basis of symptoms into asymptomatic and symptomatic subjects. Symptomatic subjects were further divided into mild, moderate, and severely symptomatic on the basis of established COVID guidelines. For the comparison of categorical variables, the analysis of Chi-square has been used. Results: The computation of Chi-square exhibited that the distribution of single deepest vertical pocket (SDP) score did not differ between asymptomatic and symptomatic subjects. Abnormal Doppler findings in the umbilical artery were found to be significantly more among subjects with severe COVID-19 symptoms compared to women with mild to moderate symptoms. Among women with abnormal Doppler, there were 6.3% vaginal and 93.7% cesarean deliveries. Mean APGAR at 1 minute and 5 minutes after birth was found to be 5.05 ± 1.09 and 3.16 ± 0.92 in asymptomatic and 5.24 ± 1.24 and 3.40 ± 1.02 in symptomatic patients, respectively. In symptomatic subjects, NICU admission was significantly more (54.0%) compared to asymptomatic subjects (16.0%). Conclusion: As the research has indicated that COVID-19-infected pregnant women may experience rapid and increasing placental insufficiency, it appears that a comprehensive assessment and management of the mother is required.


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  1. Antonakou A. The latest update on the effects of COVID-19 infection in pregnancy. Eur J Midwifery 2020;4:12. DOI: 10.18332/ejm/120973.
  2. Zeng H, Xu C, Fan J, et al. Antibodies in infants born to mothers with COVID-19 pneumonia. JAMA 2020;323(18):1848–1849. DOI: 10.1001/jama.2020.4861
  3. Cunningham FG, Leveno KJ, Bloom SL, et al. William's obstetrics. 24th edn. 2014.
  4. Madendag Y, Madendag IC, Sahin E, et al. How well do the popular ultrasonic techniques estimate amniotic fluid volume and diagnose oligohydramnios, in fact? Ultrasound Q 2019;35(1):35–38. DOI: 10.1097/RUQ.0000000000000408
  5. Stampalija T, Alfirevic Z, Gyte G. Doppler in obstetrics: evidence from randomized trials. Ultrasound Obstet Gynecol 2010;36(6):779–780. DOI: 10.1002/uog.8863
  6. Gottfredsson M. The Spanish flu in Iceland 1918. Lessons in medicine and history. Laeknabladid 2008;94(11):737–745.
  7. Anuk AT, Tanacan A, Yetiskin FDY, et al. Doppler assessment of the fetus in pregnant women recovered from COVID-19. J Obstet Gynaecol Res 2021;47(5):1757–1762. DOI: 10.1111/jog.14726
  8. Vivanti AJ, Vauloup-Fellous C, Prevot S, et al. Transplacental transmission of SARS-CoV-2 infection. Nat Commun 2020;11(1):3572. DOI: 10.1038/s41467-020-17436-6
  9. Bhide A, Acharya G, Bilardo CM, et al. ISUOG practice guidelines: use of Doppler ultrasonography in obstetrics. Ultrasound Obstet Gynecol 2013;41(2):233–239. DOI: 10.1002/uog.12371
  10. Aldemir O, Karahanoglu E, Esinler D, et al. Gynecol Obstet Reprod Med Umbilical artery Doppler findings in patients with preterm premature rupture of membranes 2014;20:3.
  11. Alfirevic Z, Stampalija T, Medley N. Fetal and umbilical Doppler ultrasound in normal pregnancy. Cochrane Database Syst Rev 2015;2015(4):CD001450. DOI: 10.1002/14651858.CD001450.pub4
  12. Tanacan A, Erol SA, Turgay B, et al. The rate of SARS-CoV-2 positivity in asymptomatic pregnant women admitted to hospital for delivery: experience of a pandemic center in Turkey. Eur J Obstet Gynecol Reprod Biol 2020;253:31–34. DOI: 10.1016/j.ejogrb.2020.07.051
  13. Liao X, Yang H, Kong J, et al. Chest CT findings in a pregnant patient with 2019 Novel Coronavirus Disease. Balkan Med J 2020;37(4):226–228. DOI: 10.4274/balkanmedj.galenos.2020.2020.3.89.
  14. Dong L, Tian J, He S, et al. Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn. JAMA 2020;323(18):1846–1848. DOI: 10.1001/jama.2020.4621
  15. Schwartz DA. An analysis of 38 pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: maternal coronavirus infections and pregnancy outcomes. Arch Pathol Lab Med 2020;144(7):799–805. DOI: 10.5858/arpa.2020-0901-SA
  16. Karimi-Zarchi M, Neamatzadeh H, Dastgheib SA, et al. Vertical transmission of coronavirus disease 19 (COVID-19) from infected pregnant mothers to neonates: a review. Fetal Pediatr Pathol 2020;39(3):246–250. DOI: 10.1080/15513815.2020.1747120
  17. Alzamora MC, Paredes T, Caceres D, et al. Severe COVID-19 during pregnancy and possible vertical transmission. Am J Perinatol 2020;37(8):861–865. DOI: 10.1055/s-0040-1710050
  18. Rabiei M, Soori T, Abiri A, et al. Maternal and fetal effects of COVID-19 virus on a complicated triplet pregnancy: a case report. J Med Case Rep 2021;15(1):87. DOI: 10.1186/s13256-020-02643-y
  19. Yu N, Li W, Kang Q, et al. No SARS-CoV-2 detected in amniotic fluid in mid-pregnancy. Lancet Infect Dis 2020;20(12):1364. DOI: 10.1016/S1473-3099(20)30320-0
  20. Ott WJ. Current perspective in antenatally surveillance ultrasound. Rev Obst Gynaecol 2003;3(1):1–18.
  21. Shanes ED, Mithal LB, Otero S, et al. Placental pathology in COVID-19. Am J Clin Pathol 2020;154(1):23–32. DOI: 10.1093/ajcp/aqaa089
  22. Chen H, Guo J, Wang C, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet 2020;395(10226):809–815. DOI: 10.1016/S0140-6736(20)30360-3
  23. Liu Y, Chen H, Tang K, et al. Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy. J Infect 2020:S0163–4453(20)30109–2. DOI: 10.1016/j.jinf.2020.02.028
  24. Kuhrt K, McMicking J, Nanda S, et al. Placental abruption in a twin pregnancy at 32 weeks’ gestation complicated by coronavirus disease 2019 without vertical transmission to the babies. Am J Obstetr Gynecol MFM 2020;2(3):100135. DOI: 10.1016/j.ajogmf.2020.100135
  25. Alfirevic Z, Stampalija T, Dowswell T. Fetal and umbilical Doppler ultrasound in high-risk pregnancies. Cochrane Database Syst Rev 2017;6(6):CD007529. DOI: 10.1002/14651858.CD007529.pub4
  26. Panahi L, Amiri M, Pouy S. Risks of Novel Coronavirus Disease (COVID-19) in pregnancy; a narrative review. Arch Acad Emerg Med 2020;8(1):e34.
  27. Juan J, Gil MM, Rong Z, et al. Effect of Coronavirus Disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome: systematic review. Ultrasound Obstet Gynecol 2020;56(1):15–27. DOI: 10.1002/uog.22088
  28. Royal College of Obstetricians Gynaecologists, Royal College of Midwives. Coronavirus infection in pregnancy: Information for healthcare professionals. https://www.rcog.org.uk/globalassets/documents/guidelines/2020-04-09- coronavirus-covid-19-infection-in-pregnancy.pdf.
  29. Fenizia C, Biasin M, Cetin I, et al. Analysis of SARS-CoV-2 vertical transmission during pregnancy. Nat Commun 2020;11(1):5128. DOI: 10.1038/s41467-020-18933-4
  30. Phoswa WN, Khaliq OP. Is pregnancy a risk factor of COVID-19? Eur J Obstet Gynecol Reprod Biol 2020;252:605–609. DOI: 10.1016/j.ejogrb.2020.06.058
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