Donald School Journal of Ultrasound in Obstetrics and Gynecology

Register      Login

VOLUME 6 , ISSUE 1 ( January-March, 2012 ) > List of Articles


Trophoblastic Diseases

Gino Varga, Ulrich Honemeyer, Kazuo Maeda

Keywords : Trophoblastic disease,Hydatidiform mole,Invasive mole,Choriocarcinoma,PSTT,ETT,B-mode,3D,Color Doppler,Power Doppler,Pulsed Doppler,Chemotherapy

Citation Information : Varga G, Honemeyer U, Maeda K. Trophoblastic Diseases. Donald School J Ultrasound Obstet Gynecol 2012; 6 (1):27-42.

DOI: 10.5005/jp-journals-10009-1224

License: CC BY-NC 4.0

Published Online: 01-12-2012

Copyright Statement:  Copyright © 2012; The Author(s).


How to cite this article

Maeda K, Kurjak A, Varga G, Honemeyer U. Trophoblastic Diseases. Donald School J Ultrasound Obstet Gynecol 2012;6(1):27-42.

PDF Share
  1. The general rules for clinical and pathological management of trophoblastic diseases (2nd ed). Tokyo: Kanehara Shuppan, 1995.
  2. Amniotic tissue in complete hydatidiform moles can be androgenetic. J Pathol 2000;191:67-70.
  3. Androgenetic origin of hydatidiform mole. Nature 1977;268(5621):633-34.
  4. Dispermic origin of XY hydatidiform mole. Nature 1981;292(5823):551-52.
  5. Characteristics of women with recurrent molar pregnancies. Gynecol Oncol 2000;78(3 pt. 1):288-92.
  6. Telomerase activity in complete hydatidiform mole. Am J Obstet Gynecol 1999;180(2 Pt. 1):328-33.
  7. Sonographic appearance of early complete molar pregnancy. J Ultrasound Med 1999;18:589-94.
  8. Philippe E, Boue JG, et al. Human triploidy association with partial hydatidiform moles and nonmolar conceptuses. Hum Pathol 1981;12(11):1016-21.
  9. DNA flow cytometric quantification and DNA polymorphism analysis in the case of a complete mole with a coexisting fetus. J Ass Reprod Genet 1999;16(5):263-67.
  10. Malignant germ cell tumors: Clinical characteristics, treatment and outcome. A report from the study group for pediatric solid malignant tumors in the Kyushu area. Japa J Pediatr Surg 2002;37:1703-06.
  11. Primary choriocarcinoma of the vulva. lnt J Gynecol Cancer 2001;11(3):251-54.
  12. Primary choriocarcinoma of the uterine cervix: clinical, MRI and color Doppler ultrasonographic study. Gynecol Oncol 1997;64(2):274-78.
  13. Primary choriocarcinoma of the stomach and pancreas: CT findings. Eur Radiol 1988;8(8):1425-28.
  14. Primary gastric choriocarcinoma: A case report and review of the literature. Arch Pathol Lab Med 2001;125(12):1601-04.
  15. Choriocarcinoma of the gallbladder: Treated with cisplatine-based chemotherapy. Med Oncol 2001;18:165-69.
  16. Pure primary choriocarcinoma of the urinary bladder with long-term survival. Urology 2000;56(5):856.
  17. Treament of chorionepithelioma of uterine cervix with hypogastric arterial infusion of amethopterin. J Jpn Obstet gynecol Soc 1966;13:245-49.
  18. Cutaneous metastasis of gestational choriocarcinoma. Int J gynecol Obstet 2002; 77(3):249-50.
  19. Intracardiac, resection of a metastatic choriocardinoma. Gynecol Oncol 2002;84 157-80.
  20. Right ventricular metastatic, choriocarcinoma obstructing inflow and outflow tract. Ann Thorac Surg 2002;73(5):1631-33.
  21. Personal communication. In: Maeda K (Ed). Gestational trophoblastic disease, Lecture in the Ian Donald Inter-University School of Medical Ultrasound, Dubrovnik, 1995.
  22. Choriocarcinoma coexistent with and intact, pregnancy: Case report and review of the literature. J Obstet Gynecol Res 1999;25:197-203.
  23. Intraplacental choriocarcinoma associated with viable pregnancy: Pathologic features and implications for the mother and infant. Pediatr Dev Pathol 1998;1(5):380-87.
  24. Advances in the understanding of placental site trophoblastic tumor. J Reprod Med 2002;47:337-41.
  25. Handbook of Gyn Oncology. New York: Mcgraw Hill, 2001.
  26. Metastatic placental site trophoblastic tumor. Report of a case with complete response to chemotherapy. J Reprod Med 2001;46(3):259-62.
  27. Metastasizing placental site trophoblastic tumor: Immunohistochemical and DNA analysis. 2 case reports and a review of the literature. Arch gynecol Obstet 1997;259(2):97-103.
  28. Placental site trophoblastic tumor: A 17-year experience at the New England Trophoblastic Disease Center. Gynecol Oncol 2001;82(3): 415-19.
  29. Placental site trophoblastic tumor (PSTT) in mother and child: first report of PSTT in infancy. Med Pediatr Oncol 2002;38(3):187-91.
  30. Placental site trophoblastic tumor: A challenging rare entity. Eur J Gynaecol Oncol 2006;27(6):545-51.
  31. Placental site trophoblastic tumor: a study of 55 cases and review of the literature emphasizing factors of prognostic significance. Gynecol Oncol 2006;100(3):511-20.
  32. Epithelioid trophoblastic tumor: Review of a rare neoplasma of the chorionic-type intermediate trophoblast. Arch Pathol Lab Med 2006;130(12):1875-77.
  33. Epithelioid trophoblastic tumor: A neoplasm distinct from choriocarcinoma and placental site trophoblastic tumor simulating carcinoma. Am J Surg Pathol 1998;22(11):1393-403.
  34. Current issues in the histopathology of gestational trophoblastic tumors. Fetal Pediatr Pathol 2010;29(1):30-44.
  35. Transvaginal color and pulsed Doppler study of uterine blood flow in the first and early second trimesters of pregnancy: normal versus abnormal. J Ultrasound Med 1994;13(1):43-47.
  36. Transvaginal color Doppler in the assessment of abnormal early pregnancy. J Perinat Med 1991;19(3):155-65.
  37. Prophylactic chemotherapy with amethopterin for the prevention if choriocarcinoma following removal of hydatidiform mole. Am J Obstet Gyncol 1968;100:270-75.
  38. Color Doppler ultrasonography in the earlier differentiation of benign molehydatidiform from malignant gestational trophoblastic disease. Acta Obstet Gynecol Scand 1998;77(8):860-62.
  39. Differential gene expression pattern between normal human trophoblast and choriocarcinoma cell lines: Downregulation of heat shock protein-27 in choriocarcinoma in vitro and in vivo. Gynecol Oncol 1999;75:(3)391-96.
  40. DNA polymorphism analysis of a pure polymorphism nongestational choriocarcinoma of the ovary: Case report. Eur J Gynecol Oncol 2000;21:153-54.
  41. Placental site trophoblastic tumor: The value of transvaginal colour and pulsed Doppler sonography (TV-CGS) in its diagnosis: Case report. Eur J Gynecol Oncol 1997;18:461-64.
  42. Placental site trophoblastic tumor diagnosed on transvaginal sonography. Ultrasound Obstet Gynecol 2009;34(2):235-36.
  43. Sonographic appearance of gestational trophoblastic disease evolving into epithelioid trophoblastic tumor. Ultrasound Obstet Gynecol 2010;36(2):249-51.
  44. Analysis of risk factors for postmolar trophoblastic disease: Categorization of risk factors and effect of prophylactic chemotherapy. Yonsei Med J 1996;37:412-19.
  45. The management of gestational trophoblastic tumors with etoposide, methotrexate, and actinomycin D. Gynecol Oncol 1997;64(1):156-59.
  46. Recent advances in gestational trophoblast disease. Hematol Oncol Clin North Am 1999;13(1):225-44.
  47. Postpartum choriocarcinoma complicated by brain and lung metastases treated successfully with EMA/CO regimen. BJOG 2000;107(9):1171-72.
  48. Resistance to multiple agent chemotherapy including cisplatin after chronic low-dosage oral etoposide. Administration in gestational choriocarcinoma. Gynecol Obstet Invest 2001;52(2):139-41.
  49. Chemoresistant choriocarcinoma cured by pulmonary lobectomy and craniotomy. Int J Gynecol Cancer 2000;10(2):165-69.
  50. Choriocarcinoma and epithelial trophoblastic tumor: successful treatment of relapse with hysterectomy and high dose chemotherapy with peripheral stem cell support: A case report. Gynecol Oncol 2002;85(1):204-08.
  51. Combination of high-dose chemotherapy, autologous bone marrow/peripheral blood stem cell transplantation, and thoracoscopic surgery in refractory nongestational choriocarcinoma of a 45XO/46XY female: A case report. Gynecol Oncol 1997;64(3):521-25.
  52. Detection of hCG in trophoblastic disease. The USA hCG reference service experience. J Reprod Med 2002;47(6):433-44.
  53. Avoiding inappropriate clinical decisions based on false-positive human chorionic gonadotropin test results. Obstet Gyecol 2002;100(5 Pt 1):1057-59.
  54. Intra-arterial infusion chemotherapy for liver metastases of testicular tumors: Report of two cases. Hinyokika Kiyo 2000;46(11): 823-27.
  55. Influence of chemotherapy for gestational trophoblastic disease on subsequent pregnancy outcome. Br J Obstet Gynaecol 1998;105(9):1032-35.
  56. Chemotherapy for gestational trophoblastic tumours hastens menopause by 3 years. Eur J Cancer 1998;34(8):1204-07.
  57. Management of placental site trophoblastic tumors. J Reprod Med 1995;43(1): 53-59.
  58. Successful treatment of malignant placental site trophoblastic tumor with combined cytostatic-surgical approach: case report and review of literature. Gynecol Oncol 1999;75(1):164-69.
  59. Case of PSTT treated with chemotherapy followed by open uterine tumor resection to preserve fertility. Gynecol Oncol 2002;87(3):303-07.
  60. Metastatic placental site trophoblastic tumor. Int J Gynecol Obst 1998;60(Suppl l):S51-55.
  61. Metastatic placental site trophoblastic tumor: Long-term remission in a patient treated with EMA/CO chemotherapy. Gynecol Oncol 1998;68(1):62-65.
  62. Prognostic factors and treatment for placental site trophoblastic tumor report of 3 cases and analysis of 88 cases. Gynecol Oncol 1999;73(2):216-22.
  63. Metastatic placental site trophoblastic tumor. Report of a case with complete response to chemotherapy. J Reprod Med 2001;46(3):259-62.
  64. Prolonged remission of recurrent, metastatic placental site trophoblastic tumor after chemotherapy. Gynecol Oncol 2000;76(1):115-17.
  65. Choriocarcinoma in the pulmonary artery treated with emergency pulmonary embolectomy. Chest 2002;121(2):654-56.
  66. An experience of stereotactic radiation therapy for primary intracranial choriocarcinoma. Tumori 2001;87(3):162-65.
  67. Controversies in the management of brain metastases: the role of chemotherapy. Forum (Genova) 2001;11(1):59-74.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.