Donald School Journal of Ultrasound in Obstetrics and Gynecology

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VOLUME 4 , ISSUE 4 ( October-December, 2010 ) > List of Articles

REVIEW ARTICLE

Ultrasonographic Evaluation of the Fetal Neural Axis

Sakshi Tomar

Keywords : Antenatal sonography,Central nervous system,Congenital anomalies

Citation Information : Tomar S. Ultrasonographic Evaluation of the Fetal Neural Axis. Donald School J Ultrasound Obstet Gynecol 2010; 4 (4):373-382.

DOI: 10.5005/jp-journals-10009-1157

License: CC BY-NC 4.0

Published Online: 00-12-2010

Copyright Statement:  Copyright © 2010; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

The central nervous system is probably the first organ system to be investigated in utero by diagnostic ultrasound. Anencephaly was the first congenital anomaly to be recognized by this technique before viability. Since then, the investigation of the fetal neural axis has steadily remained a central issue of antenatal sonography. Such an interest is explained by a number of reasons. CNS anomalies are frequent and often have a severe prognosis. In many cases they have a genetic background: consequently a large number of couples are at risk and warrant antenatal diagnosis. Modern high resolution ultrasound equipment yields a unique potential in evaluating normal and abnormal anatomy of the fetal neural axis beginning at very early stages of development.


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  1. Fetal neurosonography: Should it be routine? Should it be detailed? [Editorial]. Ultrasound Obstet Gynecol 1998;12:1.
  2. Ultrasonography in Obstetrics and Gynecology (4th ed). 277-304.
  3. Acrania: Anencephaly resulting from secondary degeneration of a closed neural tube: Two cases in the same family. J Clin Ultrasound 1991;19:230.
  4. Sensitivity and specificity of routine antenatal screening for congenital anomalies by ultrasound: The Belgian Multicentric Study. Ultrasound Obstet Gynecol 1991;1:102.
  5. Fetal cephaloceles: Diagnosis with US. Radiology 1991;180:803.
  6. Fetal ventricle: Importance in routine obstetric sonography. Radiology 1991;181:1.
  7. Exclusion of fetal ventriculomegaly with a single measurement. The width of lateral ventricular atrium. Radiology 1988;169:711.
  8. Holoprosencephaly, vol 30 Amsterdam, Elsevier, 1977.
  9. Early transvaginal sonographic diagnosis of a lobar holoprosencephaly. Prenat Diagn 1991;11:459.
  10. Agenesis of corpus callosum: Prenatal detection usually is not possible before 22 weeks of gestation. Radiology 1996;199:447.
  11. The Dandy-Walker syndrome or the so called atresia of the foramen Magendie. J Neuropathol Exp Neurol 1954;13:14.
  12. Sonography of fetal Dandy Walker Malformations. A reappraisal. Ultrasound Obstet Gynecol 1992;2:151.
  13. Differential diagnosis and outcome of fetal intracranial hypoechoic lesions. Report of 21 cases. Ultrasound Obstet Gynecol 1997;9:229.
  14. The diagnosis of fetal microcephaly. Am J Obstet Gynecol 1984;149:512.
  15. Unilateral Megalencephaly with nerve cell hypertrophy. An anatomical and quantitative histochemical study. Brain Res 1968;9:103.
  16. Clinical significance of fetal intracranial haemorrhage. Am J Obstet Gynecol 1996;175:536.
  17. Arteriovenous malformations. Location and evolution in the fetal brain. J Ultrasound Med 1991;10:361.
  18. Fetal choroid cysts and trisomy 18: Assessment of risk based on ultrasound findings and maternal age. Prenat Diagnosis 1994;14:119.
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