Donald School Journal of Ultrasound in Obstetrics and Gynecology

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VOLUME 4 , ISSUE 3 ( July-September, 2010 ) > List of Articles

REVIEW ARTICLE

Fetal Brain Vascularity Visualized by Conventional 2D and 3D Power Doppler Technology

Keywords : 2D color Doppler,3D power Doppler,3D sonography,Angiogenesis,Cerebral circulation,Early fetal circulation

Citation Information : Fetal Brain Vascularity Visualized by Conventional 2D and 3D Power Doppler Technology. Donald School J Ultrasound Obstet Gynecol 2010; 4 (3):249-258.

DOI: 10.5005/jp-journals-10009-1147

License: CC BY-NC 4.0

Published Online: 00-09-2010

Copyright Statement:  Copyright © 2010; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Significant advances have been made in accurate and reliable visualization of the cerebral circulation in normal and abnormal pregnancies. They provided the non-invasive studies of fetal cerebral angiogenesis and further development that filled some of the gaps made by neuroanatomical studies alone. The first breakthrough in the assessment of fetal circulation was development of Doppler system with purpose to obtain velocity waveforms. Continuing technical advances in Doppler ultrasound equipment, especially highly sensitive color flow imagining techniques have made it possible to study smaller anatomical parts of fetal circulation system including cerebral vascularization. Before examination of brain vascularity, anatomical vascular structure and development on the different appearance at each gestational age should be remembered as the basic knowledge. Since the development of the embryo is rapid and significant changes occur during even one week it is important to specify the stage of the embryo or fetus both by age (postmenstrual weeks and days) and by size (crownrump length (CRL) and biparietal diameter (BPD).

Introduction of three-dimensional (3D) sonography and 3D power Doppler techniques have enabled visualization of intracranial vessels. 3D power Doppler assessment particularly adds useful information in the prenatal evaluation of normal brain development, vascular malformation and tumoral vascularity.


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  1. Recent advances in the Doppler study of early fetomaternal circulation. J Perinat Med. 1993;21:419-39.
  2. Fetal choroids plexus vascularization assessed by color flow ultrasonography. J Ultrasound Med 1994;13:841-44.
  3. New data on early cerebral circulation. Prenat Neonat Med 1997;2:48-55.
  4. Transvaginal 3D and Doppler ultrasonography of the fetal brain. Semin Perinat 2001;25:38-43.
  5. Transvaginal Doppler assessment of fetal intracranial venous flow. Obstet Gynecol 1999;93:697-701.
  6. Developing brain produces an angiogenesis factor. Dev Biol 1986;83:3855-59.
  7. VEGF expression is developmentally regulated during human brain angiogenesis. Histochem Cell Biol 2003;119(3):227-32.
  8. The internal carotid artery: Cavernous, clinoid, ophthalmic and communicating segments In Diagnostic Cerebral Angiography (2nd ed): Lippincott Williams & Wilkins: Philadelphia 1999;91-93.
  9. Merce LT, et al. Structural and functional early human development assessed by three-dimensional and four-dimensional sonography. Fertil Steril 2005;84(5):1285-99.
  10. Evaluation of the carotid, aortic and umbilical blood velocity waveforms in the human fetus. In 11th Annual Conf Soc Study of Fetal Physiology; 1984:Oxford:Abstract No. C33.
  11. Transvaginal power Doppler angiography of the fetal brain. Ultrasound Obstet Gynecol 1996;8(6): 417-21.
  12. The maximum systolic velocity increases in middle cerebral artery of normal fetus from 22nd to 38th week of gestation. Acta Med Port 2006;19(2):105-08.
  13. Fetal neuroimiging. Fetal and Maternal Medicine Review 2008;19:1-31.
  14. Vascular, axonal and glial pathogenesis of periventricular leukomalacia in fetuses and neonates neuroembryology 2002;1:72-77.
  15. The management of vein of Galen aneurysmal malformations. Neurosurgery 2006;59:184-94.
  16. Aneurysms of the vein of Galen. Experience at The Hospital for Sick Children, Toronto. J Neurosurg 1982;57:316-22.
  17. Aneurysmal malformation of the vein of Galen in three patients: Clinical and radiological follow-up. Neuroradiology 1998;40:816-21.
  18. Recent improvement in outcome using transcatheter embolization techniques for neonatal aneurismal malformations of the vein of Galen. Pediatrics 1993;91:583-86.
  19. Congenital brain tumors. Surg Neurol 1984;21:597-609.
  20. Brain tumors and vein of Galen malformation. Neurology of the Newborn (4th ed). Philadelphia: WB Saunders 2001;841-56.
  21. Prenatal sonographic imaging of an immature intracranial teratoma. Fetal Diagn Ther 1999;14(4):220-22.
  22. Antepartum fetal intracranial hemorrhage, predisposing factors and prenatal sonography: A review. Am J Perinatol 1998;15:431-41.
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