Donald School Journal of Ultrasound in Obstetrics and Gynecology

Register      Login

VOLUME 4 , ISSUE 2 ( April-June, 2010 ) > List of Articles


Magnetic Resonance-guided Focused Ultrasound (MRgFUS) Treatment of Uterine Fibroid

John KF Chan

Keywords : Focused ultrasound,uterine fibroids,MRI

Citation Information : Chan JK. Magnetic Resonance-guided Focused Ultrasound (MRgFUS) Treatment of Uterine Fibroid. Donald School J Ultrasound Obstet Gynecol 2010; 4 (2):157-161.

DOI: 10.5005/jp-journals-10009-1137

License: CC BY-NC 4.0

Published Online: 01-03-2011

Copyright Statement:  Copyright © 2010; The Author(s).


Magnetic resonance-guided focused ultrasound (MRgFUS) is a new treatment modality in treating uterine fibroid. It is noninvasive and can be done as out-patient procedure. It is the least invasive treatment option other than medical treatment. Early reports have demonstrated feasibility and safety. It is efficacious in symptom improve and fibroid volume reduction. This article reviews the principle, patient selection and treatment. Results from early trial and our center are summarized.

PDF Share
  1. Physical Principles of Medical Ultrasonics (2nd ed). Chichester, UK: Wiley; 2004.
  2. A precise and fast temperature mapping using water proton chemical shift. Magn Reson Med 1995;34:814-23.
  3. Image-guided thermal therapy of uterine fibroids. Radio Graphics 2007;27:1819-26.
  4. Features influencing patient selection for fibroid treatment with magnetic resonance-guided focused ultrasound. J Vasc Interv Radiol 2007;18:681-85.
  5. Uterine leiomyomas: MR imaging guided focused ultrasound surgery results of different treatment protocols. Radiology 2007;243:885-93.
  6. Magnetic resonanceguided focused ultrasound surgery for uterine fibroids: Relationship between the therapeutic effects and signal intensity of preexisting T2-weighted magnetic resonance images. Am J Obstet Gynecol 2007;196;184-84.
  7. Gonadotrophin-releasing hormone and magnetic-resonance-guided ultrasound surgery for uterine leiomyomata. Obstet Gynecol 2006;108:49-54.
  8. Magnetic resonance guided focused ultrasound surgery of uterine fibroids. The tissue effects of GnRH agonist pre-treatment. Eur J Radiol 2006;59:163-67.
  9. MRI guidance of focused ultrasound therapy of uterine fibroids: Early results. AJR Am J Roentgenol 2004;183:1713-19.
  10. The UFSQOL, a new disease-specific symptom and health-related quality of life questionnaire for leiomyomata. Obstet Gynecol 2002;99:290-300.
  11. MR imagingguided focused ultrasound surgery of uterine leiomyomas: A feasibility study. Radiology 2003;226:897-905.
  12. Focused ultrasound treatment of uterine fibroid tumors: Safety and feasibility of a non-invasive thermoablative technique. Am J Obstet Gynecol 2003;189:48-54.
  13. Clinical outcomes of focused ultrasound surgery for the treatment of uterine fibroids. Fertil Steril 2006;85:22-29.
  14. Uterine leiomyomas: MR imaging-guided focused ultrasound surgeryresults of different treatment protocols. Radiology 2007; 243:885-93.
  15. Sustained relief of leiomyoma symptoms by using focused ultrasound surgery. Obstet Gynecol 2007;110:279-87.
  16. Full thickness abdominal burn following magnetic resonance guided focused ultrasound therapy. Burns 2005;31:1054-55.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.