Donald School Journal of Ultrasound in Obstetrics and Gynecology

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VOLUME 2 , ISSUE 2 ( April-June, 2008 ) > List of Articles

RESEARCH ARTICLE

Ultrasound Evaluation of Abnormal Early Pregnancy

Badreldeen Ahmed, Sanja Kupesic, Jose Maria Carrera

Keywords : Early pregnancy ultrasound,morphological and biometrical ultrasound examination,differentiation between normal and abnormal pregnancy

Citation Information : Ahmed B, Kupesic S, Carrera JM. Ultrasound Evaluation of Abnormal Early Pregnancy. Donald School J Ultrasound Obstet Gynecol 2008; 2 (2):87-105.

DOI: 10.5005/jp-journals-10009-1060

License: CC BY-NC 4.0

Published Online: 01-06-2008

Copyright Statement:  Copyright © 2008; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Ultrasound examination has become the “golden standard” in follow-up of the development and complications in early pregnancy. With introduction of transvaginal sonography a possibility for early morphological and biometrical ultrasound examinations has been significantly improved. The essential aim of an early pregnancy ultrasound is not only to diagnose a pregnancy, but also to differentiate between normal and abnormal pregnancy. Application of color Doppler ultrasound has enabled functional hemodynamic presentation and evaluation soon after implantation.


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  1. Ultrasound in early pregnancy. In Kurjak A (Ed): Diagnostic ultrasound in developing countries. Mladost 1986;65-75.
  2. Pathology of women's reproductive system. AGM, Zagreb, 1999.
  3. Embryonic death in early pregnancy: a new look at the first trimester. Obstet Gynecol 1994;84:294-97.
  4. Langman's Medical Embriology, 7th Williams and Wilkins, 1994.
  5. Developmental horizons in human embryo (4th issue). A review of the histogenesis of cartilage and bone. Contr Embryol Carneg Inst 949;220:150-73.
  6. G.K. The examination of the embryo and early fetus: how and by whom? Ultrasound Obstet Gynecol 1999;14:153-58.
  7. Early development of the abdominal wall, stomach and heart from the 7 to 12 weeks of gestation: a longitudinal study. Ultrasound Obstetr Gynecol 1995;6:240-49.
  8. Diagnostic and therapeutical decision-making with transvaginal sonography for first trimester spontaneous abortion, clinically thought to be complete or incomplete. Contraception 1998; 57: 393-97.
  9. Early embryonic mortality in women. Fertil Steril 1982; 38: 447-53.
  10. Infertility and early pregnancy loss. Am J Obstet Gynecol 1995;172: 1510-17.
  11. The epidemiology of repeated abortion. In Beard RW and Bishop F (Eds): Early pregnancy loss: mechanism and treatment. New York: Springer-Verlag 1988;9-17.
  12. Detection of retained products of conception following spontaneous abortion in the first trimester. J Ultrasound Med 1991;10: 387-95.
  13. Z. Evaluation of the accuracy of transvaginal sonography for the assessment of retained products of conception after spontaneous abortion. Gynecol Obstet Invest 1998;45:190-93.
  14. Sonography of obstetric and gynecologic emergencies. AJR Am J Roentgenol 2000;174:641.
  15. Ultrasonography in obstetric and gynecologic emergencies. Radiol Clin North Am 1994;32:1005.
  16. Transvaginal sonography in the detection of retained products of conception after first-trimester spontaneous abortion. J Clin Ultrasound 2002; 30:428-32.
  17. Transvaginal duplex Doppler sonography in bleeding patients suspected on having residual trophoblastic tissue. Obstet Gynecol 1993; 81:507-11.
  18. Endovaginal ultrasound and Doppler findings after first-trimester abortion. Radiology 1993;186:87-91.
  19. Accurate diagnosis of postabortial placental remanant by sonohysterography and color Doppler sonographic studies. Gynecol Obstet Invest 1997;43:131-34.
  20. Transvaginal color Doppler ultrasonography in the management of first-trimester spontaneous abortion. Eu J Obstet Gynecol Reprod Bio 2002; 102:83-87.
  21. Diagnostics of spontaneous abortion. In Kurjak A (Eds): Ultrasound in Gynecology and Obstetrics. Zagreb: Art Studio Azinovic 2000;314-21.
  22. In Speroff L, Glass R H, Kase NG (Eds): Clinical Gynecologic Endocrinology and Infertility. London: Williams and Wilkins 1999;1043-55.
  23. Moderate maternal alcohol consumption and risk of spontaneous abortion. Epidemiology 1997;8:509-14.
  24. Abnormal vaginal flora in the first trimester, but not full blown bacterial vaginosis, is associated with preterm birth. Prenat Neonat Med 1998;3:558-93.
  25. Doppler studies of subchorionic hematomas in early pregnancy. In Chervenak F, Kurjak A (Eds): Current Perspectives on the Fetus as a Patient. Carnforth, UK: Parthenon Publishing 1996;33-39.
  26. Repeated fetal losses associated with antiphospholipid antibodies: a collaborative randomized trial comparing prednizone with low-dose heparin treatment. Am J Obstet Gynecol 1992;166:1318-23.
  27. Randomized controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies. Br Med 1997;314,253-57.
  28. Doppler assessment of the intervillous blood flow in normal and abnormal early pregnancy. Ultrasound Obstet Gynecol 1997;89:252-56.
  29. Assessment of uterine artery blood flow in normal first trimester pregnancies and those complicated by uterine bleeding; Ultrasound Obstet Gynecol 2002;19(4):366-70.
  30. First-trimester, three-dimensional transvaginal ultrasound volumetry in normal pregnancies and spontaneous miscarriages. Ultrasound Obstet Gynecol 2002;19:575-79.
  31. Early diagnosis of pregnancy failure with transvaginal sonography. Am J Obstet Gynecol 1988;159-408.
  32. Doppler Assessment of the intervillous blood flow in normal and abnormal early pregnancy. Ultrasound Obstet Gynecol 1997;2:252-56.
  33. Subchorionic hematomas in early pregnancy: clinical outcome and blood flow patterns. J Matern Fetal Med 1996;5:41-44.
  34. Early pregnancy hemodynamics assessed by transvaginal color Doppler. In Chervenak F, Kurjak A (Eds): The Fetus as a Patient. Carnforth UK: Parthenon Publishing 1994;435:55.
  35. Ultrasonographic assessment of early pregnancy complication. In Jurkovic D, Jauniaux E (Eds): Ultrasound and early pregnancy Carnforth, UK: Parthenon Publishing 1995;53-64.
  36. Blood flow studies in normal and abnormal pregnancy. In Kurjak A, Kupesic S (Eds): An Atlas of Transvaginal Color Doppler. London: Parthenon Publishing 2000;41-51.
  37. Abruptio placentae: From early pregnancy to term. In Chervenak F, Kurjak A (Eds): The Fetus as a Patient. Carnforth UK: Parthenon Publishing 1996;433-44.
  38. Intrauterine hematoma: an ultrasound study of threatened abortion. Br J Obstet Gynecol 1981;88:47-50.
  39. Sonography of pregnancies with first-trimester bleeding and viable embryo: a study of prognostic indicators by logistic regression analysis. Ultrasound Obstet Gynecol 1996;7:65-69.
  40. Physiology of uteroplacental and embryonic circulation. In Kurjak A (Ed): Textbook of Perinatal Medicine. Parthenon Publishing 1998;482-90.
  41. A close look at the embryonic development with the high frequency transvaginal transducer. Am J Obstet Gynecol 1988;159:676-81.
  42. Early detection of intrauterine pregnancy with ultrasound. 1988;10.
  43. Transvaginal sonography of Early intrauterine pregnancy. In Fleischer AC, Manning FA, Jeanty P, Romero R (Eds): Sonography in Obstetrics and Gynecology Principles and Practice (sixth edition) The McGraw-Hill Companies 2001;61-88.
  44. Small sac size in the first trimester: a predictor of poor fetal outcome. Radiology 1991;178:375-77.
  45. Relationship of initial chorionic sac diameter to abortion and abortus karyotype based in new growth curves for the 16th to 49th postovulation day. Hum Reprod 1994;9:559-65.
  46. Threatened abortion: Sonographic distinction of normal and abnormal gestational sac. Radiology 1986;158:397-400.
  47. Ultrasonographic differentiation of the gestational sac of early intrauterine pregnancy and pseudogestational sac of ectopic pregnancy. Radiology 1983;146:755-59.
  48. Early diagnosis of normal pregnancy with transvaginal ultrasound. Radiology 1988;167:383-85.
  49. Distinguishing normal from abnormal gestational sac growth in early pregnancy. J Ultrasound Med 1987;6:23-27.
  50. Pseudogestational sacs: Doppler US differentiation from normal or abnormal intrauterine pregnancies. Radiology 1990;176:359-64.
  51. Transvaginal and pulsed Doppler study of uterine blood flow in the first and early second trimesters of pregnancy: normal versus abnormal. J Ultrasound Med 1994;13:43-47.
  52. Color Doppler imaging in the assessment of uteroplacental blood flow in the abnormal first trimester intrauterine pregnancies: An attempt to define etiologic mechanisms. J Ultrasound Med 1992;11:41-44.
  53. Three-dimensional sonoembryology. Ultrasound Rev Obstet Gynecol 2001;1:111-19.
  54. Endovaginal appearance of the yolk sac in pregnancy: normal growth and usefulness as a predictor of abnormal pregnancy. Radiology 1992;183,115-18.
  55. Vascularization of yolk sac and vitteline duct in normal pregnancy studied by transvaginal color Doppler. J Perinat Med 1994;22:433-40.
  56. Ultrasonic and Doppler studies of human yolk sac. In Chervenak F, Kurjak A (Eds): The Fetus as a Patient. Carnforth UK: Parthenon Publishing 1996;345-47.
  57. Morphology and significance of the human yolk sac. In Barnea E (Ed): The first twelve weeks of gestation. Heidelberg: Springer 1992;192-16.
  58. Endovaginal sonography of the first trimester of pregnancy. Proceedings of the 3rd International Perinatal and Gynecological Ultrasound Symposium Ottawa, Ontario; 1994;1-25.
  59. Abdominal ultrasound examination of the first trimester fetus. Am J Obstet Gynecol 1988;159:165-75.
  60. Parallel Doppler assessment of yolk sac and intervillous circulation in normal pregnancy and missed abortion. Placenta 1998;19:619-23.
  61. Early hemodynamics studied by transvaginal color Doppler. Prenatal and Neonatal Medicine 1996;1:38-49.
  62. Yolk sac calcification: A sonographic finding associated with intrauterine embryonic demise in the first trimester. Radiology 1988;166:109-16.
  63. Color Doppler sonographic assessment of placental circulation in the first trimester of normal pregnancy. J Ultrasound Med 1996;15:135-42.
  64. Uteroplacental and luteal circulation in normal first-trimester pregnancies: Doppler ultrasonographic and morphologic study. Am J Obstet Gynecol 1996;174:768-75.
  65. Intervillous circulation in all three trimesters of normal pregnancy assessed by color Doppler. J Perinat Med 1997;25:373-80.
  66. Three-dimensional Sonography for Assessment of Morphology and Vascularization of the Fetus and Placenta. J Soc Gynecol Investig 2002;9:186-202.
  67. Blood flow studies in early pregnancy. In Kurjak A, Kupesic S (Eds): Color Doppler in obstetrics, gynecology and infertility. Art Studio Azinovic-Medison Zagreb-Seoul 1999;87-108.
  68. Crown-rump length in the chromosomally abnormal fetuses at 10 to 13 weeks’ gestation. Am J Obstet Gynecol 1995;172:32-35.
  69. The significance of crown-rump length measurement for predicting adverse pregnancy outcome of threatened abortion. Ultrasound Obstet Gynecol 2001;17: 510-12.
  70. Transvaginal US: Demonstration of cardiac activity in embryos less than 5.0 mm in crown-rump length. Radiology 1990;176:71-74.
  71. Prospective comparison of vaginal and abdominal sonography in normal early pregnancy. J Ultrasound Med 1991;10:63-67.
  72. First trimester bradycardia: A sign of impending fetal loss. J Ultrasound Med 1989;8:561-63.
  73. First-Trimester Obstetric Emergencies: Spectrum of sonographic findings. J Clin Ultrasound 2002;3:161-77.
  74. Slow embryonic heart rate in early first trimester: indicator of poor pregnancy outcome. Radiology 1994;192:343.
  75. The embryo as a patient: early pregnancy loss. In Chervenak, F., Kurjak, A. (eds.) The Fetus as a Patient. Carnforth UK: Parthenon Publishing. 1996;345-47.
  76. Long term prognosis of pregnancies complicated by slow embryonic heart rates in early first trimester. J Ultrasound Med 1999;18:537-41.
  77. Ultrasound Evaluation During the First Trimester of Pregnancy. In Callen PW (Ed): Ultrasound in Obstetrics and Gynecology 4th edition Sounders Company 2000;105-45.
  78. Enlarged amniotic cavity: A new sonographic sign of early embrionic death. AJR Am J Roentgenol 1992;158:359-62.
  79. The “empty amnion”: a sign of early pregnancy failure. J Ultrasound Med 1995;14:117-21.
  80. Fetal nuchal translucency screening for chromosomal defects in first trimester of pregnancy. Br Med J 1992;034:867-69.
  81. Screening for fetal trisomies by maternal age and fetal nuchal translucency thickness at 10-14 weeks of gestation. Br J Obstet Gynecol 1995;102:957-62.
  82. Nuchal translucency measurement in normal fetuses. Obstet Gynecol 1995;86:994.
  83. Nuchal translucency measurements: Frequency distribution and changes with gestation in a general population. Br J Obstet Gynecol 1995;103:1201.
  84. Increased nuchal translucency as a marker for fetal chromosomal defects. N Eng J Med 1997;337:1654-58.
  85. Antenatal screening for Down's syndrome. Lancet 1998;352:1631-32.
  86. Nuchal translucency and the acceptance of invasive prenatal chromosomal diagnosis in women aged 35 and older. Obstet Gynecol 2001;97:916-20.
  87. Three-dimensional transvaginal ultrasound improves measurement of nuchal translucency. J Perinat Med 1999;27:97-102.
  88. Three-dimensional ultrasound markers of chromosomal anomalies. In Kurjak A, Kupesic S (Eds): Clinical application of 3D sonography. Parthenon Publishing London NY. 2000;143-50.
  89. Three-dimensional ultrasound for nuchal translucency measurement at 10-14 weeks of gestation. In Kurjak A, Kupesic S (Eds): Clinical application of 3D sonography. Parthenon Publishing London NY. 2000;151-54.
  90. Recognition of fetal subdiaphragmatic venous vestibulum essential for fetal venous Doppler assessment. Pediatr Res 1992;32:338-41.
  91. Regulation of blood flow through the ductus venosus. J Dev Physiol 1980;2:219-38.
  92. Cardiovascular responses to acute, severe hemorrhage in fetal sheep. J Dev Physiol 1991;15:189-97.
  93. Doppler velocimetry of the ductus venosus in the first trimester of pregnancy. In Kurjak A, Chervenak FA, Carrera JM (Eds): The Embryo as a Patient, Parthenon Publishing Group, New York London 2001;181-85.
  94. Reference ranges for fetal venous and atrioventricular blood flow parameters. Ultrasound Obstet Gynecol 1994;4:381-90.
  95. Ductus venosus blood velocity changes in fetal cardiac diseases. J Matern Fetal Invest 1993;3:15-20.
  96. Ductus venosus blood velocity and the umbilical circulation in seriously growth-retarded fetus. Ultrasound Obstet Gynecol 1994;4:109-14.
  97. Assessment of fetal compromise by Doppler ultrasound investigation on the fetal circulation. Arterial, intracardiac and venous blood flow velocity studies. Circulation 1995;91:129-38.
  98. The role of ductus venosus blood flow assessment in screening for chromosomal abnormalities at 10-16 week of gestation. Ultrasound Obstet Gynecol 2001;17:295-300.
  99. Increased nuchal translucency: possible involvement of early cardiac failure. Ultrasound Obstet Gynecol 1997;10:265-68.
  100. Transient increase in nuchal translucency thickness and reversed end-diastolic ductus venosus flow in a fetus with trisomy 18. Ultrasound Obstet Gynecol 1997;10:397-99.
  101. Ductus venosus index: a new method for evaluating right ventricular preload in the second trimester fetus. Ultrasound Obstet Gynecol 1993;3:338-42.
  102. First trimester ductus venosus velocimetry in relation to nuchal translucency thickness and fetal karyotype. Fetal Diagn Ther 2002;17:52-57.
  103. First trimester umbilical artery pulsatility index in fetuses presenting enlarged nuchal translucency. Prenat Diagn 2000;20:701-04.
  104. Reversed end-diastolic flow in first trimester umbilical artery: An ominous new sign for fetal outcome. Am J Obstet Gynecol 2001;185:204-07.
  105. Absence of nasal bone in fetuses with trisomy 21 at 11-14 weeks of gestation: an observational study. Lancet 2001;358 (9294):1665-67.
  106. Prenatal ultrasound diagnosis of nasal bone abnormalities in the three fetuses with Down syndrome. Am J Obstet Gynecol 2002;186:139-41.
  107. Nuchal translucancy and congenital heart defects: heart failure or not? Ultrasound Obstet Gynecol 2000;16:30-36.
  108. The sonographic approach to the detection of fetal cardiac anomalies in the early pregnancy. Ultrasound Obstet Gynecol 2002;19:360-65.
  109. First trimester umbilical cord diameter: a novel marker of fetal aneuploidy. Ultrasound Obstet Gynecol 2002;19:235-39.
  110. Aneuploidy screening: ultrasound versus biochemistry. Ultrasound Rev Gynecol 2002;2:221-28.
  111. Combining ultrasound and biochemistry in first trimester screening for Down's syndrome. Prenat Diagn 1997;17:821-29.
  112. Early pregnancy screening for fetal aneuploidy with serum markers and nuchal translucency. Prenat Diagn 1999;19:458.62.
  113. A screening program for trisomy 21 at 10-14 weeks using fetal nuchal translucency, maternal serum free ƒÀ-human chorionic gonadotropin and pregnancyassociated plasma protein-A. Ultrasound Obstet Gynecol 1999;13:231-37.
  114. Screening for trisomy 13 by fetal nuchal translucency, maternal serum free ƒÀ-HCG and PAPP-A at 10-14 weeks of gestation. Prenat Diagn 2000;20:411-16.
  115. Maternal serum free ƒÀ-HCG and PAPP-A in fetal sex chromosome defects in first trimester. Prenat Diagn 2000;20:390-94.
  116. Early screening for chromosomal abnormalities: new strategies combining biochemical, sonographic and Doppler parameters. Prenat Neonat Med 2001;6:95-102.
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