VOLUME 17 , ISSUE 4 ( October-December, 2023 ) > List of Articles
Toshiyuki Hata, Aya Itoh, Riko Takayoshi, Takahito Miyake, Mika Sugihara, Koichiro Shimoya, Hirotake Nishimura, Kazuhiko Ino
Keywords : Case report, Coexistent fetus, Color Doppler, Early first-trimester diagnosis, HDlive, HDlive Silhouette, Partial hydatidiform mole
Citation Information : Hata T, Itoh A, Takayoshi R, Miyake T, Sugihara M, Shimoya K, Nishimura H, Ino K. Early First-trimester Diagnosis of Partial Hydatidiform Mole with Coexistent Live Fetus in Twin Pregnancy. Donald School J Ultrasound Obstet Gynecol 2023; 17 (4):369-372.
DOI: 10.5005/jp-journals-10009-2002
License: CC BY-NC 4.0
Published Online: 28-12-2023
Copyright Statement: Copyright © 2023; The Author(s).
We present a case of partial hydatidiform mole with a coexistent live fetus in a twin pregnancy diagnosed early in the first trimester of pregnancy. At 6 weeks and 4 days of gestation, an early-stage nonhydropic mole (massive lobulated masses with intrauterine anechoic fluid collection) in one gestational sac (GS) and a viable embryo (crown-rump length = 4 mm) in another GS were identified. An inhomogeneous solid mass adjacent to the GS containing the viable embryo was noted at 8 weeks and 4 days. Blood flow was evident at the periphery of the solid mass with numerous focal vesicles at 10 weeks and 2 days. HDlive depicted numerous focal small vesicles in the solid mass and a viable fetus in the GS. HDlive Silhouette clearly showed a viable fetus in the GS adjacent to the solid mass containing numerous small focal vesicles and an umbilical cord attached to the normal placenta. The parents decided to terminate the pregnancy at 11 weeks and 3 days of gestation. The pathological diagnosis was a partial hydatidiform mole with a coexistent fetus (PHMCF). Chromosome analysis revealed 46, XY of the fetus, and 69, XXX of the hydatidiform mole. To the best of our knowledge, this is the first report of diagnosing a PHMCF early in the first trimester of pregnancy. Color Doppler and HDlive Silhouette might be useful adjunctive modalities to diagnose a partial hydatidiform mole with the coexistent fetus.
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