Donald School Journal of Ultrasound in Obstetrics and Gynecology

Register      Login

VOLUME 17 , ISSUE 2 ( April-June, 2023 ) > List of Articles

CASE REPORT

Fetal Cardiac Tumor: HDlive Flow Silhouette with Spatiotemporal Image Correlation and HDlive Features

Toshiyuki Hata, Tomomi Kawahara, Takahito Miyake, Kei Hayata

Keywords : Fetal cardiac tumor, HDlive, HDlive flow, HDlive flow silhouette, Tortuous ductus arteriosus, Spatiotemporal image correlation

Citation Information : Hata T, Kawahara T, Miyake T, Hayata K. Fetal Cardiac Tumor: HDlive Flow Silhouette with Spatiotemporal Image Correlation and HDlive Features. Donald School J Ultrasound Obstet Gynecol 2023; 17 (2):117-120.

DOI: 10.5005/jp-journals-10009-1969

License: CC BY-NC 4.0

Published Online: 05-07-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Abstract

We present HDlive flow silhouette with spatiotemporal image correlation (STIC) and HDlive features of multiple fetal cardiac tumors at 28 weeks and 2 days of gestation. Fetal echocardiography showed multiple cardiac tumors in four chambers. Tortuous ductus arteriosus was also noted. HDlive flow revealed the spatial relationship between the tortuous ductus arteriosus and aorta. HDlive flow silhouette with STIC and HDlive clearly revealed intraventricular tumors and spatial blood flow dynamics of cardiac chambers and great vessels. HDlive depicted intraventricular tumor movements in real-time. There was no manifestation of cardiac failure. Fetal cardiac rhabdomyoma was strongly suspected. Cardiac tumors resolved 2 months later after delivery with the use of everolimus.


HTML PDF Share
  1. Mackie AS, Kozakewich HP, Geva T, et al. Vascular tumors of the heart in infants and children: case series and review of the literature. Pediatr Cardiol 2005;26(4):344–349. DOI: 10.1007/s00246-004-0717-2
  2. Groves AM, Fagg NL, Cook AC, et al. Cardiac tumours in intrauterine life. Arch Dis Child 1992;67(10 Spec No):1189–1192. DOI: 10.1136/adc.67.10_spec_no.1189
  3. Bonnamy L, Perrotin F, Megier P, et al. Fetal intracardiac tumor(s): prenatal diagnosis and management. Three case reports. Eur J Obstet Gynecol Reprod Biol 2001;99(1):112–117. DOI: 10.1016/s0301-2115(01)00337-2
  4. Yuan SM. Fetal primary cardiac tumors during perinatal period. Pediatr Neonatol 2017;58(3):205–210. DOI: 10.1016/j.pedneo.2016.07.004
  5. Gamzu R, Achiron R, Hegesh J, et al. Evaluating the risk of tuberous sclerosis in cases with prenatal diagnosis of cardiac rhabdomyoma. Prenat Diagn 2002;22(11):1044–1047. DOI: 10.1002/pd.464
  6. Jóźwiak S, Kotulska K. Are all prenatally diagnosed multiple cardiac rhabdomyomas a sign of tuberous sclerosis? Prenat Diagn 2006;26(9):867–869. DOI: 10.1002/pd.1506
  7. Chen J, Wang J, Sun H, et al. Fetal cardiac tumors: echocardiography, clinical outcome and genetic analysis in 53 cases. Ultrasound Obstet Gynecol 2019;54(1):103–109. DOI: 10.1002/uog.19108
  8. Hata T, Yan F, Dai SY, et al. Real-time 3-dimensional echocardiographic features of fetal cardiac tumor. J Clin Ultrasound 2007;35(6):338–340. DOI: 10.1002/jcu.20324
  9. Hata T, Mashima M, Ito M, et al. Three-dimensional HDlive rendering images of the fetal heart. Ultrasound Med Biol 2013;39(8):1513–1517. DOI: 10.1016/j.ultrasmedbio.2013.03.027
  10. Hata T, Koyanagi A, Yamanishi T, et al. Success rate of five cardiac views using HDlive flow with spatiotemporal image correlation at 18-21 and 28-31 weeks of gestation. J Perinat Med 2020;48:384–388. DOI: 10.1515/jpm-2019-0434
  11. Hata T, Koyanagi A, Kawahara T, et al. HDlive Flow silhouette with STIC for assessment of fetal cardiac structures at 12 – 14+6 weeks of gestation. J Perinat Med 2021;50(3):313–318. DOI: 10.1515/jpm-2021-0252
  12. Ito M, AboEllail MAM, Yamamoto K, et al. HDlive Flow silhouette mode and spatiotemporal image correlation for diagnosing congenital heart disease. Ultrasound Obstet Gynecol 2017;50(3):411–415. DOI: 10.1002/uog.17519
  13. Araujo Júnior E, Tonni G, Bravo-Valenzuela NJ, et al. Assessment of fetal congenital heart diseases by 4-dimensional ultrasound using spatiotemporal image correlation. Ultrasound Q 2018;34(1):11–17. DOI: 10.1097/RUQ.0000000000000328
  14. Shen Q, Shen J, Qiao Z, et al. Cardiac rhabdomyomas associated with tuberous sclerosis complex in children. From presentation to outcome. Herz 2015;40(4):675–678. DOI: 10.1007/s00059-014-4078-1
  15. Wang CC, Wang CY, Lai YJ, et al. Prenatal diagnosis of tuberous sclerosis complex using fetal ultrasonography and magnetic resonance imaging and genetic testing. Taiwan J Obstet Gynecol 2018;57(1):163–165. DOI: 10.1016/j.tjog.2017.12.029
  16. Boitor Borza D, Popa Stanila R, Zaharie G, et al. Fetal cardiac rhabdomyomas as a sonographic sign of tuberous sclerosis complex – a diagnosis not to be missed. A pictorial essay. Med Ultrason 2022;24(3):364–368. DOI: 10.11152/mu-3318
  17. Krueger DA, Northrup HInternational Tuberous Sclerosis Complex Consensus Group;. Tuberous sclerosis complex surveillance and management: recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference. Pediatr Neurol 2013;49(4):255–265. DOI: 10.1016/j.pediatrneurol.2013.08.002
  18. Demir HA, Ekici F, Yazal Erdem A, et al. Everolimus: a challenging drug in the treatment of multifocal inoperable cardiac rhabdomyoma. Pediatrics 2012;130(1):e243–e247. DOI: 10.1542/peds.2011-3476
  19. Mohamed I, Ethier G, Goyer I, et al. Oral everolimus treatment in a preterm infant with multifocal inoperable cardiac rhabdomyoma associated with tuberous sclerosis complex and a structural heart defect. BMJ Case Rep 2014;2014:bcr2014205138. DOI: 10.1136/bcr-2014-205138
  20. Wagner R, Riede FT, Seki H, et al. Oral everolimus for treatment of a giant left ventricular rhabdomyoma in a neonate-rapid tumor regression documented by real time 3D echocardiography. Echocardiography 2015;32(12):1876–1879. DOI: 10.1111/echo.13015
  21. Benson CB, Brown DL, Doubilet PM, et al. Increasing curvature of the normal fetal ductus arteriosus with advancing gestational age. Ultrasound Obstet Gynecol 1995;5(2):95–97. DOI: 10.1046/j.1469-0705.1995.05020095.x
  22. Tseng JJ, Jan SL. Fetal echocardiographic diagnosis of isolated ductus arteriosus aneurysm: a longitudinal study from 32 weeks of gestation to term. Ultrasound Obstet Gynecol 2005;26(1):50–56. DOI: 10.1002/uog.1859
  23. Hata T, Kawahara T, Konishi M, et al. Isolated tortuous ductus arteriosus in a fetus: HDlive flow with spatiotemporal image correlation (STIC) study. J Perinat Med 2023. DOI: 10.1515/jpm-2022-0522
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.