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VOLUME 17 , ISSUE 1 ( January-March, 2023 ) > List of Articles

ORIGINAL RESEARCH ARTICLE

Three-dimensional Power Doppler Ultrasonography Evaluation of Maternal Orbital Perfusion in Pregnancies with Gestational Diabetes Mellitus

Riko Takayoshi, Toshiyuki Hata, Yasunari Miyagi, Takahito Miyake, Kenji Kanenishi

Keywords : Gestational diabetes mellitus, Maternal orbital perfusion, Maternal orbital vascular sonobiopsy, Normal pregnancy, Three-dimensional power Doppler ultrasound

Citation Information : Takayoshi R, Hata T, Miyagi Y, Miyake T, Kanenishi K. Three-dimensional Power Doppler Ultrasonography Evaluation of Maternal Orbital Perfusion in Pregnancies with Gestational Diabetes Mellitus. Donald School J Ultrasound Obstet Gynecol 2023; 17 (1):5-10.

DOI: 10.5005/jp-journals-10009-1966

License: CC BY-NC 4.0

Published Online: 14-04-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Abstract

Objective: Determine the level of maternal orbital perfusion in gestational diabetes mellitus (GDM) pregnant women using maternal orbital vascular sonobiopsy (MOVS) and three-dimensional (3D) power Doppler ultrasound methods. Methods: The use of 3D power Doppler ultrasonography (3D-PDUS) for maternal orbital perfusion, together with virtual organ computer-aided analysis (VOCAL) histogram analysis, was carried out in 33 pregnancies between 25 and 40 weeks of gestation, including 18 cases of normal pregnancy (control) and 15 cases of gestational diabetes. The 3D power Doppler indices, such as the vascularization index (VI), flow index (FI), and vascularization FI (VFI), were calculated in both orbits of the individual group. The average value of each index for the two orbits was evaluated for further investigation. Both inter and intraobserver agreements of 3D-PDUS were examined. Results: In the Bland–Altman test, the mean percentage difference and 95% limits of intra and interobserver agreements for VI, FI, and VFI were 0.0803% (7.3417, -7.181) and -0.6823% (10.8095, -12.1742), -0.4816% (6.0624, -7.0256) and 0% (9.0746, -8.8384), and 0.0058% (2.6937, -2.6821) and -0.2892% (3.8910, -4.4694), respectively. The correlation for all three 3D-PD indices, that is, VI, FI, and VFI, was higher than 0.75 (0.7832–0.9749). The VI, FI, and VFI levels between control and GDM pregnancies did not change significantly. Conclusion: Our findings suggest that MOVS, which was assessed using 3D-PDUS and VOCAL histogram analysis, can offer fresh perspectives on observing maternal orbital perfusion in both healthy and dysfunctional pregnancies.

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