Role of Three-dimensional Power Doppler Angiography in Assessment of Perifollicular Ovarian Vascularity in Patients Undergoing In Vitro Fertilization: A Single Center Experience
Khushali Gandhi, Sugandha Goel
IVF outcome, Number of follicles, Power doppler angiography, Three dimensional
Citation Information :
Gandhi K, Goel S. Role of Three-dimensional Power Doppler Angiography in Assessment of Perifollicular Ovarian Vascularity in Patients Undergoing In Vitro Fertilization: A Single Center Experience. Donald School J Ultrasound Obstet Gynecol 2018; 12 (3):162-167.
Introduction: Ovarian blood flow plays a vital role in ovarian follicular development in In Vitro fertilization (IVF) cycle. Perifollicular color mapping with three-dimensional (3D) power Doppler angiography (PDA) is a reliable technique for predicting IVF success.
Objective: Single-center prospective study, with an aim to investigate correlation between 3D PDA parameters and success of IVF cycles.
Methods: Ovulation induction was done using a long protocol with gonadotrophins and GnRH agonist in 94 infertile women. With the help of 3D PDA, on the day of HCG administration, ovarian volume (OV), number of follicles (NF), vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were calculated. The success of IVF outcome in these patients was noted.
Results: The OV, VI, FI, VFI, and NF were significantly higher in women who conceived following IVF. IVF outcome can be presumed by NF and VI. NF was the only independent parameter predicting a number of retrieved oocytes, mature oocytes, fertilized oocytes and number of grade 4 embryos.
Conclusion: Three-dimensional USG and PDA is an easy and quick modality for ovarian blood flow assessment and prediction of success of IVF cycle. Positive correlation was identified between 3D PDA parameters and IVF laboratory parameters along with subsequent IVF success.
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