Donald School Journal of Ultrasound in Obstetrics and Gynecology

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VOLUME 11 , ISSUE 2 ( April-June, 2017 ) > List of Articles

RESEARCH ARTICLE

Oxidative Status of Saliva and Plasma in Diabetic Children

Selma Porovic, Hrvoje Juric, Senka M Dinarevic

Keywords : Advanced oxidation protein products,Children, Diabetes,Oxidative status,Plasma,Saliva,Total antioxidant capacity

Citation Information : Porovic S, Juric H, Dinarevic SM. Oxidative Status of Saliva and Plasma in Diabetic Children. Donald School J Ultrasound Obstet Gynecol 2017; 11 (2):169-173.

DOI: 10.5005/jp-journals-10009-1517

License: CC BY-NC 4.0

Published Online: 00-06-2017

Copyright Statement:  Copyright © 2017; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim

The objective of this study was to determine the oxidative status of saliva and plasma in diabetic children, by analyzing advanced oxidation protein products (AOPPs) and total antioxidant capacity (TAC).

Materials and methods

Study included 60 patients with diabetes mellitus type I (DMT1) aged 12.45 ± 2.65 years, and 40 healthy age-matched controls. The AOPP and TAC of the plasma and saliva samples were determined using a commercial QuantiChrom™ Antioxidant Assay Kit (DTAC-100) for TAC determination, and Immunodiagnostic AG [enzyme-linked immunosorbent assay kit for AOPP].

Results

Values of salivary and plasma AOPP were lower in diabetic patients than in healthy controls, while value of TAC was clinically and significantly higher in plasma of controls, and clinically higher in saliva of healthy control group, compared with diabetic patients. Average value of hemoglobin A1c (HbA1c) was 7.58 ± 0.85%.

Conclusion

Results of this study showed that diabetes mellitus as a condition, with well-controlled HbA1c, has no influence on AOPP levels in saliva and plasma, while TAC levels of saliva and plasma are lower in diabetic patients, which means that DMT1 has an influence on the TAC.

How to cite this article

Porovic S, Juric H, Dinarevic SM. Oxidative Status of Saliva and Plasma in Diabetic Children. Donald School J Ultrasound Obstet Gynecol 2017;11(2):169-173.


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