Donald School Journal of Ultrasound in Obstetrics and Gynecology

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VOLUME 1 , ISSUE 3 ( July-September, 2007 ) > List of Articles


Three-dimensional Ultrasound of the Fetal Brain

Armando Pintucci, Vincenzo, D Addario, Vincenzo Pinto, Luca Di Cagno

Keywords : Three-dimensional ultrasound,fetal brain,brain malformations

Citation Information : Pintucci A, Vincenzo, Addario D, Pinto V, Cagno LD. Three-dimensional Ultrasound of the Fetal Brain. Donald School J Ultrasound Obstet Gynecol 2007; 1 (3):17-25.

DOI: 10.5005/jp-journals-10009-1104

License: CC BY-NC 4.0

Published Online: 01-09-2008

Copyright Statement:  Copyright © 2007; The Author(s).


Three-dimensional ultrasound is the most innovating and attracting modality in the field of ultrasound imaging and represents a superb tool to perform an accurate fetal neuroscan. Once the fetal brain has been scanned, it is then possible to “navigate” in the stored volume choosing among the multiple scanning planes on the three orthogonal spatial axes. Last generation 3D equipments have multiple software facilities which are extremely useful to correctly evaluate the fetal brain such as the multiplanar view, the tomographic ultrasound imaging (TUI), the volume contrast imaging in the C plane (VCI-C plane), the volume calculation, the surface rendering, the 3D color and power Doppler. Thanks to these imaging modalities it is possible to evaluate the finest anatomical details of the developing brain and to increase the diagnostic accuracy when an abnormal sonographic finding of the fetal brain is recognized during the routine examination.

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  1. Imaging the fetal brain in the second and third trimesters using transvaginal sonography. Obstet Gynecol 1991;77:27-32.
  2. Three-dimensional transvaginal neurosonography of the fetal brain: ‘navigating’ in the volume scan. Ultrasound Obstet Gynecol 2000;16:307-13.
  3. Fetal neuroimaging with new technology. Ultrasound Review Obstet Gynecol 2002;2:178-81.
  4. Three-dimensional imaging of the brain cavities in human embryos. Ultrasound Obstet Gynecol 1995;5:228-32.
  5. Alobar holoprosencephaly at 9 weeks gestational age visualized by two-and three-dimensional ultrasound. Ultrasound Obstet Gynecol 2000;15:62-5.
  6. Three-dimensional ultrasound evaluation of the fetal brain: the three horn view. Ultrasound Obstet Gynecol 2000;16:302-6.
  7. Diagnosis of midline anomalies of the fetal brain with the three-dimensional median view. Ultrasound Obstet Gynecol 2006;27:522-9.
  8. The fetal cerebellar vermis: anatomy and biometric assessment using volume contrast imaging in the C-plane (VCI-C). Ultrasound Obstet Gynecol 2005;26:622-7.
  9. Assessment of fetal cerebellar volume using three-dimensional ultrasound. Ultrasound Med Biol 2000;26:981-8.
  10. Posterior fossa and vermian morphometry in the characterization of fetal cerebellar abnormalities: a prospective three-dimensional ultrasound study. Ultrasound Obstet Gynecol. 2006;27:482-9.
  11. The assessment of normal fetal brain volume by 3-D ultrasound. Ultrasound Med Biol 2003;29:1267-72.
  12. Three-dimensional sonographic measurement of normal fetal brain volume during the second half of pregnancy. Am J Obstet Gynecol 2004;190:275-80.
  13. How early are fetal cerebral sulci visible at prenatal ultrasound and what is the normal pattern of early fetal sulcal development? Ultrasound Obstet Gynecol 2004;24:706-15.
  14. Sonographic developmental milestones of the fetal cerebral cortex: a longitudinal study. Ultrasound Obstet Gynecol 2006;27:494-502.
  15. Transvaginal 3D and Doppler ultrasonography of the fetal brain. Semin Perinatol 2001;25:38-43.
  16. Three-dimensional sonographic description of the fetal frontal bones and metopic suture. Ultrasound Obstet Gynecol 2005;26:618-21.
  17. Three-dimensional sonography of prenatal skull base development. Ultrasound Obstet Gynecol. 2007;29:372-7.
  18. Craniofacial variability index in utero: a three-dimensional ultrasound study. Ultrasound Obstet Gynecol 2007;29:258-64
  19. Examination of the fetal brain by transabdominal three-dimensional ultrasound: potential for routine neurosonographic studies. Ultrasound Obstet Gynecol 2006;27:503-8.
  20. The midsagittal view of the fetal brain: a useful landmark in recognizing the cause of fetal cerebral ventriculomegaly. J Perinat Med 2005;33:423-7.
  21. Structural and functional early human development assessed by three-dimensional and four-dimensional sonography. Fertil Steril 2005;84:1285-99.
  22. Normal standards for fetal neurobehavioral developments— longitudinal quantification by four-dimensional sonography. J Perinat Med. 2006;34:56-65.
  23. Neurosonography in the second half of fetal life: a neonatologist's point of view. J Perinat Med 2006;34:437-46.
  24. Behavior of an anencephalic fetus studied by 4D sonography. J Matern Fetal Neonatal Med. 2005;17:165-8.
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